| Characteristic | Detail |
|---|---|
| Generic Name | Irbesartan |
| Brand Name | Avapro |
| Dosage Form | 150 mg, 300 mg tablets |
| Pharmacologic Category | Angiotensin II Receptor Blocker |
| Indications | Hypertension, Nephropathy in Type 2 Diabetes |
| Administration | Oral |
| Learn More About Irbesartan | |
Common Brand Name
Irbesartan is widely known in the pharmaceutical market. The brand name Avapro is often associated with this angiotensin II receptor blocker (ARB). Avapro targets high blood pressure and diabetic nephropathy. It gained FDA approval and is prescribed globally. Its prominence in managing hypertension makes it a staple in medical circles.
Avapro offers multiple dosages. Options like Irbesartan 150 mg and 300 mg are typical. This variety allows tailored treatment. The flexibility in dosages suits diverse patient needs. Prescribing physicians balance efficacy and tolerability through these choices.
Avapro is not unique in the ARB class. However, it distinguishes itself in specific indications. Its profile for treating diabetic kidney disease is notable. This niche adds to its reputation as a reliable treatment option. Physicians trust Avapro for its targeted action and established outcomes.
Correct Use
Using Irbesartan necessitates precision. Dosing must align with individual patient profiles. Patients take Irbesartan orally, often once daily. It can be ingested with or without food. Consistent timing enhances drug effectiveness. Adhering to a regular schedule maximizes therapeutic benefits.
The usual starting dose is 150 mg. This dose suits most hypertensive patients. If control remains inadequate, titration to 300 mg may occur. Adjustment depends on patient response and tolerance. Physicians carefully monitor for optimum blood pressure control.
Special populations require tailored approaches. Renal function impacts dosing decisions. In impaired renal patients, cautious dose adjustment is critical. Elderly patients also need careful consideration. Their sensitivity to ARBs might differ. Detailed consultation with healthcare providers ensures safe usage.
Irbesartan Contraindications
Specific conditions contraindicate Irbesartan use. Known hypersensitivity to any component bars its use. Patients with hereditary conditions like angioedema should avoid Irbesartan. These allergies trigger potentially severe reactions.
Pregnancy is a significant contraindication. Irbesartan is classified under pregnancy category D. It poses risks to fetal development. Women of childbearing potential must employ effective contraception. If pregnancy occurs, immediate discontinuation is essential. Risk to the fetus outweighs benefits.
Patients with bilateral renal artery stenosis should avoid Irbesartan. This condition poses risks for acute renal failure. Close medical supervision is necessary if therapy is deemed unavoidable. Such cases demand rigorous risk-benefit analysis.
Cautions with Other Medicines
Irbesartan interacts with other drugs. Concomitant use with potassium supplements or potassium-sparing diuretics requires caution. These combinations can lead to hyperkalemia. Regular monitoring of potassium levels is crucial.
Using Irbesartan with NSAIDs may impact renal function. Patients with compromised renal status face increased risks. Monitoring renal function periodically is advisable. Communication between healthcare providers and patients is vital.
Combining Irbesartan with lithium calls for vigilance. The interaction may increase lithium toxicity. Serum lithium levels need frequent checks. Adjusting lithium dosage ensures safety.
Side Effects
Like any drug, Irbesartan has potential side effects. Some patients experience dizziness. This effect typically arises when standing up. Slow positional changes can minimize this discomfort.
Fatigue is another possible side effect. It often diminishes as the body adjusts. Monitoring for persistent tiredness is prudent. It ensures that it remains within manageable limits.
More severe reactions warrant immediate attention. Angioedema, though rare, can occur. Swelling of face, lips, or throat signifies an emergency. Swift medical intervention is necessary.
Overall, Irbesartan is well tolerated. Most side effects are mild and temporary. Regular follow-ups help manage any arising concerns. Effective communication with healthcare providers enhances patient experience.
Irbesartan for Sale Online
Access to Irbesartan 300 mg online is common. Many platforms list it among their offerings. Ensuring the credibility of these sites is essential. Buyers must verify licensing and regulatory compliance. This diligence prevents potential risks.
Online purchases offer convenience. They cater to patients with limited mobility or tight schedules. However, professional consultation is still necessary. Proper guidance ensures safe and effective use.
Prescription validity is crucial. Legitimate online pharmacies require valid prescriptions. This regulation maintains patient safety. Unauthorized sources might compromise drug quality and authenticity.
Purchasing medications online requires caution. Trustworthy platforms enhance patient access. They streamline processes while safeguarding health standards. Consulting healthcare professionals remains indispensable.
| Research | Source |
|---|---|
| Effects on Renal Function | NCBI Study |
| Hypertension Management | AHA Journal |
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